Jobs at ICON plc

Manages oncology clinical trial sites through qualification, initiation, monitoring, activation, and close-out. Ensures data integrity, subject safety, inspection readiness, regulatory compliance, and adherence to protocols, GCP, SOPs, and applicable regulations. Reviews risk indicators, resolves issues, develops CAPA plans, supports IRB and regulatory submissions, trains site staff, and maintains site relationships. Requires solid tumor oncology monitoring experience and up to 50% travel.

Conduct remote and on-site monitoring for oncology clinical trials, ensuring data integrity, patient safety, protocol compliance, inspection readiness, and regulatory adherence. Manage site communications, essential documents, IRB/EC submissions, risk indicators, CAPA plans, training, site activation, feasibility, and close-out activities. Lead site engagement and mentor less experienced CRAs while supporting regulatory inspections.

Conduct clinical trial monitoring for early-stage oncology studies, including site qualification, initiation, monitoring, and close-out visits. Ensure protocol compliance, data integrity, and patient safety; collaborate with investigators and site staff; resolve data queries; and support clinical study documentation. Requires at least two years of Clinical Research Associate experience, oncology monitoring expertise, a scientific or healthcare degree, and willingness to travel up to 50% within the assigned region.

Manage day-to-day clinical trial operations, including planning, timelines, budgets, protocols, stakeholder relationships, regulatory compliance, vendor selection, risk management, and clinical deliverables. Support cross-functional teams and develop team members while ensuring high-quality study outcomes. The role requires a relevant university degree, therapeutic-area expertise, clinical trial management experience, and approximately 25% travel.

Lead clinical data science initiatives supporting clinical trial analysis and strategic decision-making. Responsibilities include designing data science strategies, identifying analytical requirements, overseeing statistical models and tools, mentoring team members, and communicating insights to stakeholders. The role requires clinical research data analysis experience, statistical software expertise, data visualization skills, leadership, collaboration, and approximately 15% travel.

Conducts clinical trial site qualification, initiation, monitoring, and close-out visits. Ensures protocol compliance, data integrity, and patient safety; collaborates with investigators and site staff; reviews data and resolves queries; and contributes to study documentation, protocols, and clinical study reports. Requires at least two years of CRA experience, scientific or healthcare education, strong organizational and communication skills, and approximately 60% travel.

Conduct site management and monitoring for oncology clinical trials, including qualification, initiation, interim, and close-out visits. Ensure data integrity, subject safety, inspection readiness, regulatory compliance, and essential document reconciliation. Manage site relationships, feasibility, activation, IRB/EC submissions, risk indicators, and CAPA plans. Train site staff on protocols, GCP, SOPs, and regulations, while supporting inspections and mentoring junior CRAs. The role requires solid tumor oncology trial expertise and travel up to 50%.

Program and manage real-world healthcare datasets from claims and EMR sources. Clean, transform, normalize, and prepare analysis-ready data; create data dictionaries and programming documentation; build dashboards; and support research teams with analytics and programming for real-world evidence generation.

Manages multiple healthcare improvement initiatives across timelines, budgets, workstreams, risks, deliverables, and stakeholder relationships. Coordinates Medical Affairs, Legal, compliance, health systems, professional societies, research institutes, and other partners. Tracks spending and milestones, supports governance meetings, synthesizes performance data, maintains project dashboards and collaboration tools, conducts landscape analyses, and identifies process improvements. Requires healthcare systems knowledge, quality improvement exposure, and CRO or pharma project management experience.

Conduct clinical trial site qualification, initiation, monitoring, and close-out visits for oncology studies. Ensure protocol compliance, data integrity, and patient safety; collaborate with investigators and site staff; resolve data queries; and support preparation and review of study documentation. Requires at least two years of Clinical Research Associate experience, oncology monitoring experience, scientific or healthcare education, ICH-GCP knowledge, and willingness to travel 60–75% within the region.

Leads clinical outcome assessment (COA) research programs, including PRO, ClinRO, PerfO, and ObsRO development and validation. Designs qualitative and psychometric research, supports clinical trial protocols and statistical plans, prepares regulatory documents, develops COA strategies, and publishes findings. Requires collaboration with cross-functional teams, regulators, patients, caregivers, payers, and external partners across multiple therapeutic areas.

The Senior Clinical Project Manager will lead and manage clinical projects, ensure successful execution and delivery, mentor team members, and develop project documentation, while collaborating with stakeholders and staying current with industry trends.

Manage and monitor clinical trial sites including qualification, initiation, monitoring, and close-out visits. Ensure protocol compliance, data integrity, patient safety, query resolution, and contribute to study documentation and reports.

Leads clinical data science project teams supporting the setup, maintenance, integration, quality control, and closure of clinical trial systems. The role involves client and vendor coordination, technical documentation review, CRF quality review, timeline and budget tracking, system integration oversight, sales support, and internal user acceptance testing. Candidates need clinical data management experience, relational database knowledge, data flow diagramming skills, project management capabilities, protocol interpretation expertise, strong communication skills, and a bachelor's degree.

Coordinate and execute sponsor contracts and change orders for early-phase clinical research projects. Responsibilities include reviewing contractual terms, budgets, payment schedules, and project documents; collaborating with legal, sales, finance, operations, and project teams; analyzing financial implications; maintaining Salesforce records and contract files; supporting client negotiations; and managing multiple deadlines while ensuring accurate quality-control submissions.

Oversee clinical trial sites and ensure protocol, regulatory, and GCP compliance. Conduct site visits, assess performance, resolve issues, support site staff, and maintain data integrity and participant safety. Collaborate with cross-functional teams on data collection and reporting, train site personnel and CRAs, and manage relationships with stakeholders. The role requires extensive CRA experience, advanced relevant education, strong monitoring and organizational skills, and travel of at least 60%.

Manages clinical investigator relationships and site strategy across clinical trials, supporting investigator qualification, enrollment, protocol understanding, risk planning, inspection readiness, vendor oversight, and study closeout. Uses site performance insights to improve recruitment, feasibility, protocol design, and data delivery. Requires oncology expertise and substantial collaboration with medical, clinical, study delivery, vendor, and field teams. The role involves regional investigator engagement and frequent travel across the Mid-Atlantic and Southeast.

Monitor clinical trials including site qualification, initiation, monitoring, and close-out visits; ensure protocol compliance, data integrity, and patient safety; review and resolve data queries; collaborate with investigators and contribute to study documentation and reports.

Conduct and oversee clinical study site activities for Phase II–IV dermatology and rare disease trials. Responsibilities include site identification, initiation, monitoring, close-out, regulatory and ethics submissions, documentation, query management, feasibility assessments, cost efficiency, and potential CRA mentoring. Requires strong knowledge of ICH-GCP, medical data review, bilingual German and English communication, and willingness to travel internationally and domestically at least 60% of the time.

Monitor and manage clinical trial sites including qualification, initiation, monitoring, and close-out visits; ensure protocol compliance, data integrity, and patient safety; perform data review and query resolution; collaborate with investigators and site staff; contribute to study documentation and clinical study reports.