Senior Internal Auditor (Dallas or Phoenix Hybrid)

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary
We are seeking an experienced and motivated Senior Internal Auditor to join our growing Internal Audit team. In this role, you will play a critical part in strengthening the Company’s control environment, leading Sarbanes-Oxley (SOX) compliance efforts, and advising the business on risks and control design.This is an excellent opportunity for a technically strong auditor who enjoys partnering with the business, taking ownership of audit engagements, and contributing to continuous improvement initiatives across SOX, finance, and operations.
Job Responsibilities

• Lead and execute risk-based and integrated audit engagements, including SOX, operational, and compliance audits.
• Serve as a key contributor to the Company’s SOX compliance program, including walkthroughs, design & documentation, and control testing.
• Develop and maintain audit documentation such as process narratives, risk and control matrices, audit programs, and workpapers.
• Identify control gaps, assess root causes, and partner with management on remediation plans.
• Perform operational and integrated audits to assess process efficiency and policy compliance.
• Coordinate with external auditors and internal stakeholders to support audit requests.
• Communicate audit results through clear written reports and presentations.
• Track audit issues and remediation status and escalate as needed.
• Support annual audit planning and risk assessment activities.
• Leverage data analytics and emerging technologies to enhance audit effectiveness.

Required Qualifications

• Bachelor’s degree in accounting, finance, or a related field.
• 3+ years of experience in public accounting, internal audit, or combination.
• Strong understanding of SOX and internal control frameworks (e.g., COSO).
• Experience leading audit engagements or major workstreams.
• Excellent communication and organizational skills.
• Excellent analytical and problem-solving skills.
• Strong attention to detail and accuracy.
• Ability to work independently and as part of a team.
• Capacity to handle multiple tasks and meet deadlines.
• Ability to gather and interpret operational and financial data, prepare high quality audit workpapers and reports, and deliver results collaboratively across departments.
• Proficient in Microsoft Office Suite (Excel, Word, PowerPoint)
• Professional certification or progress toward certification (e.g., CPA, CIA).

Preferred Qualifications

• Experience in life sciences, biotechnology, healthcare, or laboratory environments.
• Experience with audit management tools such as AuditBoard.
• Exposure to data analytics, automation, or AI-enabled audit tools.
• Big Four or large public accounting firm experience.

Physical Demands

• Must possess ability to sit and/or stand for long periods of time.
• Ability to lift up to 15 pounds.
• The majority of work is performed in a desk/cubicle environment.

Training

• All job specific, safety, and compliance training are assigned based on the job functions associated with this employee.

Other

• Willingness to work shift work and overtime.
• Job may require occasional weekends, evenings, and/or holidays or travel.

Conditions of Employment:  Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.